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Eli Lilly and Company

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FDA approves Eli Lilly’s Inluriyo-Verzenio combination for ESR1-mutated breast cancer

The United States Food and Drug Administration has approved Inluriyo with Verzenio for a genetically defined form of advanced breast cancer after endocrine therapy. In a 159-patient analysis, median progression-free survival reached 11.1 months with the combination versus 5.5 months with Inluriyo alone, expanding Eli Lilly's ability to pair two medicines from its own oncology portfolio.
Eli Lilly’s retatrutide moves closer to a planned 2027 U.S. filing after completing its core Phase 3 programme for obesity, knee pain and sleep apnea. Representative image.
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Retatrutide development: Phase 3 results, 2027 FDA filing, TRIUMPH trials and what comes next

Eli Lilly and Company’s retatrutide programme has completed the core Phase 3 clinical package supporting planned submissions for obesity, knee osteoarthritis pain and obstructive sleep apnea. The investigational triple hormone receptor agonist is moving toward a U.S. filing in the first quarter of 2027 while additional studies test diabetes, cardiovascular and kidney outcomes, liver disease, chronic pain, maintenance treatment and its performance against tirzepatide.
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Eli Lilly targets autoimmune pipeline with $2.875bn Merida Biosciences acquisition

Eli Lilly is paying up to $2.875 billion for privately held Merida Biosciences only about 17 months after the biotech launched with $121 million. The lead asset remains in Phase 1, making the transaction less a conventional pipeline purchase than a bet that selectively eliminating disease-causing antibodies can open a new class of autoimmune and allergy medicines.