FDA advances Sarepta Therapeutics’ ELEVIDYS for Duchenne muscular dystrophy treatment

FDA advances Sarepta Therapeutics’ ELEVIDYS for Duchenne muscular dystrophy treatment

In a promising development for the treatment of rare diseases, Sarepta Therapeutics, Inc. (NASDAQ:SRPT), a frontrunner in precision genetic medicine, announced that the U.S. Food and Drug Administration (FDA) has accepted and filed the company’s efficacy supplement to the Biologics License Application (BLA) for ELEVIDYS (delandistrogene moxeparvovec-rokl), marking a pivotal moment in the battle against […]

FDA committee backs approval of Sarepta Therapeutics’ SRP-9001 for DMD

FDA committee backs approval of Sarepta Therapeutics’ SRP-9001 for DMD

Sarepta Therapeutics’ SRP-9001 (delandistrogene moxeparvovec) has received the backing of the Cellular, Tissue and Gene Therapies Advisory Committee (CTGTAC) of the US Food and Drug Administration (FDA) for accelerated approval for Duchenne muscular dystrophy (DMD). The FDA committee voted 8 to 6 in favor of the investigational gene therapy for the treatment of ambulatory patients […]

Sarepta Therapeutics to seek FDA accelerated approval for SRP-9001 in DMD

Sarepta Therapeutics to seek FDA accelerated approval for SRP-9001 in DMD

Sarepta Therapeutics said that it plans to file a biologics license application (BLA) with the US Food and Drug Administration (FDA) to seek accelerated approval for SRP-9001 (delandistrogene moxeparvovec) for the treatment of ambulant individuals with Duchenne muscular dystrophy (DMD). The investigational DMD gene therapy is being co-developed with Roche under a $2.85bn deal signed […]

Roche signs $2.85bn deal with Sarepta for SRP-9001 DND gene therapy

Roche signs $2.85bn deal with Sarepta for SRP-9001 DND gene therapy

Roche has signed a licensing deal worth up to $2.85 billion with Sarepta Therapeutics for the exclusive ex-US commercial rights to the latter’s SRP-9001 (AAVrh74.MHCK7.micro-dystrophin), an investigational gene therapy for Duchenne muscular dystrophy (DMD). As per the agreement terms, Sarepta Therapeutics will get an upfront payment made up of $750 million in cash and $400 […]