Xencor, Inc., a clinical-stage biopharmaceutical company specializing in engineered antibodies for cancer treatment, saw its stock rise by 26% to $20.39 on Monday following substantial updates on its research and development (R&D) efforts and promising results from a Phase 1 dose-escalation study. Despite the recent surge, the stock remains down about 5% for the year, […]
CARsgen Therapeutics Holdings Limited, a prominent player in the field of CAR T-cell therapies, has announced the successful completion of patient enrollment for its pivotal Phase II clinical trial of Satri-cel (satricabtagene autoleucel). This advanced autologous CAR T-cell product candidate targets Claudin18.2 and aims to treat patients with advanced gastric and gastroesophageal junction cancers (GC/GEJ) […]
Exscientia plc (Nasdaq: EXAI), a pioneer in AI-driven drug discovery, has reached a strategic milestone by acquiring full ownership of the oral CDK7 inhibitor program from GT Apeiron, taking control of the promising compound GTAEXS617 (‘617) along with all associated intellectual property. Under the terms of the agreement, Exscientia will pay GT Apeiron $10 million […]
Roche (SIX: RO, ROG; OTCQX: RHHBY) has announced disappointing results from the phase II/III SKYSCRAPER-06 study, aimed at evaluating the efficacy of tiragolumab plus Tecentriq (atezolizumab) and chemotherapy in treating non-squamous non-small cell lung cancer. The study did not meet its primary endpoints of progression-free survival (PFS) and overall survival (OS), signaling a setback in […]
MediLink Therapeutics (Suzhou) Co., Ltd., a prominent clinical-stage biotech company, has entered into a significant new strategic collaboration with BioNTech SE, a leader in next-generation immunotherapy. This collaboration involves an exclusive option for BioNTech to secure a global license to utilize MediLink’s innovative TMALIN antibody-drug conjugate (ADC) platform for several novel targets. A Lucrative Collaboration […]
In a significant development for cancer research, Innovent Biologics, Inc. (HKEX: 01801), a leading biopharmaceutical company renowned for its innovative medicines in oncology, cardiovascular and metabolic diseases, autoimmune disorders, ophthalmology, and other major diseases, has announced the presentation of preclinical data on multiple novel bispecific antibodies and antibody-drug conjugates (ADCs) from its oncology pipeline at […]
Roche’s subsidiary, Genentech, has announced a significant breakthrough with the US Food and Drug Administration (FDA) approval of Tecentriq (atezolizumab). This new approval marks a pivotal development in the fight against extensive stage small cell lung cancer (ES-SCLC), as the monoclonal antibody will now be used in combination with chemotherapy as a first-line treatment for […]
Kite Pharma has clinched the US FDA approval for its Car T therapy Yescarta (axicabtagene ciloleucel) for treating a type of lymphatic cancer in patients who have no more treatment options left and are staring at a dire prognosis.
In a significant development for lymphoma treatment, Kite Pharma, a subsidiary of Gilead Sciences, has received approval from the U.S. Food and Drug Administration (FDA) for its chimeric antigen receptor T cell (CAR T) therapy, Yescarta (axicabtagene ciloleucel). This new therapy is now approved for adult patients in the United States with relapsed or refractory […]