Regeneron says REGEN-COV monoclonal antibodies active against Omicron, Delta and other variants

Regeneron Pharmaceuticals said that the monoclonal antibodies of its REGEN-COV cocktail are active against all known variants of concern of Covid-19, including Omicron and Delta.

According to the US biotech company, REGEN-COV, which comprises the casirivimab and imdevimab antibodies, has diminished potency against Omicron, but is active against the Delta variant, which is more prevailing in the US.

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Regeneron Pharmaceuticals said that it is confirming that multiple ‘next generation’ monoclonal antibodies from its collection of fully human monoclonal antibodies targeting SARS-CoV-2 are active against the Omicron (B.1.1.529) and Delta (B.1.617.2) variants, in addition to the other variants of concern.

Regeneron says REGEN-COV monoclonal antibodies active against Omicron, Delta and other variants
Regeneron says REGEN-COV monoclonal antibodies active against Omicron, Delta and other variants. Image courtesy of Gerd Altmann from Pixabay .

The biotech company said that subject to regulatory discussions, it expects the Covid-19 drug to enter the clinic in Q1 2022.

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REGEN-COV is yet to be approved by the US Food and Drug Administration (FDA). However, it has emergency use authorization for the treatment and post-exposure prophylaxis in some high risk individuals.


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