Wall Street bets on biotech and AI: Reddit, Exelixis, Rocket Lab all explode

U.S. stock market top gainers on May 14, 2025: See why Newegg, Rigetti, Reddit, and Exelixis surged as investor sentiment turned risk-on. Read full analysis.

The U.S. stock market witnessed a strong rally on May 14, 2025, with top-performing stocks showing double-digit gains across sectors such as e-commerce, biotech, AI computing, clean energy, and satellite communications. Investor sentiment turned decisively bullish following a softer-than-expected core CPI print, dovish commentary from Federal Reserve officials, and early signs of tariff de-escalation between the U.S. and China. Institutional flows tilted toward growth and innovation, with retail momentum fueling smaller-cap names. Below is a detailed breakdown of all 24 top U.S. stock market gainers for May 14, including performance analysis, volume data, valuation metrics, and investor sentiment.

Why Did Newegg Commerce Stock Surge Over 53%?

Newegg Commerce, Inc. (NASDAQ: NEGG) soared 53.65% to $7.99, becoming the day’s highest gainer on the U.S. stock market. The stock traded on 2.45 million shares, dramatically higher than its three-month average of 43,622. With a market cap of just $155.6 million and no current P/E ratio due to losses, Newegg’s surge appears driven by short covering, algorithmic interest, and speculative retail positioning following improved e-commerce sales data in April. The company had previously declined over 75% in the past year, and Tuesday’s rally marked a sharp reversal in trend.

What Boosted Exelixis Shares by 21%?

Exelixis, Inc. (NASDAQ: EXEL) gained 20.84%, closing at $44.65 on a volume spike to 12.83 million shares, nearly five times its average. With a market capitalization of $12.3 billion and a trailing P/E of 25.37, the biopharma company is benefiting from upbeat sentiment around its oncology pipeline. Analysts cited fresh preclinical data supporting its XL092 compound as a potential immunotherapy enhancer, reigniting M&A speculation in mid-cap biotech. Institutional interest has returned as the stock is up nearly 75% over the past 12 months.

How Did Rigetti Computing Gain Nearly 18%?

Rigetti Computing, Inc. (NASDAQ: RGTI) climbed 17.99% to $11.64, fueled by speculative excitement around quantum computing. With 132 million shares traded—well above its average of 48.4 million—Rigetti drew significant retail volume. The company, which is yet to report earnings or generate consistent revenue, now commands a $3.34 billion market cap and is up over 700% in the past year. Analysts attribute the move to AI-quantum convergence themes gaining popularity in hedge fund circles.

What Drove Everus Construction Stock Higher?

Everus Construction Group, Inc. (NASDAQ: ECG) rose 17.27% to $60.30. Volume hit 3.73 million shares, far above its 747,000 average. The infrastructure builder is benefiting from ongoing bipartisan support for federal transportation and housing bills. The company’s $3.07 billion market cap and 21.46 P/E suggest it remains a moderate-growth value play in a capital-heavy industry.

Why Did Super Micro Computer Rebound?

Super Micro Computer, Inc. (NASDAQ: SMCI) rebounded 15.71% to $45.00 on massive volume of 165.9 million shares, more than double its three-month average. Despite being a key AI hardware supplier, SMCI is down 59% YTD amid valuation corrections and margin pressures. However, with renewed optimism on AI infrastructure demand, the stock found support from both retail and institutional re-entry, signaling possible bottoming formation.

What Explains Tencent Music’s 15.66% Jump?

Tencent Music Entertainment Group (NYSE: TME) climbed 15.66% to $16.99, with 21.9 million shares traded. The Chinese streaming company, valued at $24.93 billion and trading at a P/E of 28.80, benefited from Beijing’s continued easing of internet sector regulations and growing international user base. Institutional investors appear to be reallocating into China-tech names after a long period of underweighting.

Why Is Oklo Inc. Rallying Again?

Oklo Inc. (NYSE: OKLO) gained 15.55% to $37.01. The nuclear tech firm saw 39.1 million shares traded against an average of 12.6 million. With a $5.15 billion market cap, Oklo’s stock has jumped over 211% in 2025, amid growing political and energy sector interest in small modular reactors (SMRs). The rally follows news of a potential new U.S. Department of Energy grant to support advanced nuclear research.

What’s Behind EchoStar’s 15% Surge?

EchoStar Corporation (NASDAQ: SATS) advanced 15.19% to $22.78, fueled by strong demand in satellite infrastructure. The firm traded 7.3 million shares versus a 2.78 million average and now holds a $6.53 billion market cap. Analysts cited a pending contract with a major defense contractor and improving satellite broadband ARPU as key catalysts.

Why Did Reddit Shares Jump Over 11%?

Reddit, Inc. (NYSE: RDDT) rose 11.06% to $125.32, with volume spiking to 20.6 million. Now valued at $23.12 billion and with a 25.11 P/E, Reddit has been expanding monetization strategies, including ad partnerships and premium memberships. The rally reflects sustained optimism following better-than-expected Q1 earnings and accelerating MAUs.

What Propelled Rocket Lab Over 10%?

Rocket Lab USA, Inc. (NASDAQ: RKLB) gained 10.54% to $24.13. Volume reached 36.6 million shares. With a $11.13 billion market cap, the satellite launcher is riding momentum from a successful commercial payload launch and a rumored strategic partnership with the U.S. Space Force. The 403% 52-week return indicates strong long-term interest.

Why Is ZoomInfo Back in Focus?

ZoomInfo Technologies Inc. (NASDAQ: ZI) rose 10.27% to $10.31 as traders bought into cost-cutting-fueled recovery hopes. Volume doubled to 14.9 million, while the company’s valuation stands at $3.77 billion. Despite being down 24% in the past year, the company’s SaaS tools for sales intelligence remain in demand as enterprise software spending stabilizes.

What’s Fueling Regencell Bioscience’s Continued Rise?

Regencell Bioscience Holdings (NASDAQ: RGC) climbed 9.86% to $342.99. With just 44,859 shares traded, the rally reflects low-float volatility. The Hong Kong-based biotech now has a $4.46 billion market cap and is up nearly 6,000% over the past year, though fundamentals remain opaque. Institutions remain cautious despite heavy speculative retail buying.

Why Did Tonix Pharmaceuticals Rise?

Tonix Pharmaceuticals Holding Corp. (NASDAQ: TNXP) added 9.42% to $22.08. Although volume stayed under its 3-month average, the rally aligns with broader biotech sentiment. With a $151 million market cap, the stock’s 96% annual decline makes it a high-risk bounce candidate.

What’s Driving PVH Corp.’s Comeback?

PVH Corp. (NYSE: PVH) jumped 8.42% to $87.28. Volume more than doubled to 3.78 million. The apparel firm’s P/E stands at 8.27, reflecting deep value. Analysts attribute the surge to strong spring merchandise sell-through and leaner inventories across wholesale channels.

Why Did Liberty Global Stocks Rise?

Liberty Global’s dual listings (LBTYK and LBTYA) rose 7.94% and 7.60% respectively. Trading volumes were elevated for both tickers as speculation increased about further asset sales in European markets. The company’s $3.18 billion market cap remains pressured by high leverage and declining subscriber bases.

Why Is Wingstop Gaining Momentum?

Wingstop Inc. (NASDAQ: WING) rose 6.97% to $306.25. The fast-casual brand saw 1.63 million shares traded, reflecting investor enthusiasm around consistent same-store sales and unit expansion. Its $8.54 billion market cap and 51.38 P/E signal confidence in premium franchise growth models.

What’s Driving ZIM’s 6.84% Rally?

ZIM Integrated Shipping Services (NYSE: ZIM) closed up 6.84% at $18.28. Volume reached 11.5 million shares. With a P/E under 1, the stock is benefiting from rising shipping rates and new cargo route openings amid ongoing Red Sea supply chain tensions.

Why Did Sunrun and Enphase Rally?

Sunrun Inc. (NASDAQ: RUN) rose 6.72% to $12.70, while Enphase Energy (NASDAQ: ENPH) gained 5.79% to $48.27. Both solar names rallied on news of extended federal tax credits and a recovery in California residential installations. Institutional buying in clean energy ETFs lifted sentiment.

What’s Lifting Alignment Healthcare?

Alignment Healthcare, Inc. (NASDAQ: ALHC) rose 6.12% to $14.91. The Medicare Advantage provider has seen consistent enrollment growth. Its $2.95 billion market cap reflects investor optimism around senior-focused healthcare services and CMS reimbursement clarity.

How Did Archer and NuScale Benefit?

Archer Aviation Inc. (NYSE: ACHR) jumped 6.09% to $11.84, and NuScale Power Corporation (NYSE: SMR) added 6.01% to $22.94. Both companies are emerging green tech plays—Archer in eVTOL aircraft and NuScale in SMRs. U.S. Department of Energy support and venture capital backing helped sustain institutional interest.

Why Is Sea Limited Gaining?

Sea Limited (NYSE: SE) rose 5.87% to $163.18. The Singapore-based e-commerce and gaming company has rebounded over 124% in the past year. Investors cheered its recent margin improvement in Shopee and cost discipline across Garena, supported by softening dollar trends.

What’s Fueling Dynatrace’s 5.86% Gain?

Dynatrace Inc. (NYSE: DT) gained 5.86% to $53.50. The observability software firm saw 7 million shares traded and is now worth $16 billion. Growth in AI-powered monitoring solutions and resilience in cloud budgets helped drive sentiment.

Institutional Sentiment and Outlook

Institutional buying was concentrated in AI, infrastructure, and clean tech. Hedge funds appeared to rotate out of defensive utilities into more cyclical and growth-oriented bets. With inflation softening and rate hike probabilities falling, investors appear more willing to deploy risk capital.

Looking ahead, key market catalysts include retail earnings, Fed minutes, and updates on U.S.–China trade negotiations. Sector-specific momentum may persist in AI infrastructure, biotech M&A, and advanced energy solutions.


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