Sobi and Apellis Pharmaceuticals, Inc. have announced encouraging one-year outcomes from the phase 2 NOBLE study, investigating the efficacy of systemic pegcetacoplan for treating post-transplant recurrence of C3 glomerulopathy (C3G) and primary immune complex membranoproliferative glomerulonephritis (IC-MPGN). These findings were presented at the European Renal Association (ERA) Congress, held from May 23-26 in Stockholm, Sweden. […]
Sonofi and Sobi have secured the approval of the US Food and Drug Administration (FDA) for their Altuviiio [Antihemophilic Factor (Recombinant), Fc-VWF-XTEN Fusion Protein-ehtl] for hemophilia A treatment. Altuviiio, previously known as efanesoctocog alfa, is a first-in-class, high-sustained factor VIII replacement therapy indicated for routine prophylaxis and on-demand treatment to control bleeding episodes, as well […]
Swedish Orphan Biovitrum (Sobi) said that the first patient has been dosed with Doptelet (avatrombopag) in a phase 3 trial for the treatment of immune thrombocytopenia (ITP) in pediatric patients. Avatrombopag is a thrombopoietin receptor agonist (TPO-RA). Its phase 3 study – AVA-PED-301 will assess the efficacy, safety, and pharmacokinetics in the treatment of the […]
