vTv Therapeutics and OnKure part ways, dissolving pivotal cellular drug agreement

vTv Therapeutics and OnKure part ways, dissolving pivotal cellular drug agreement

vTv Therapeutics, a clinical-stage biopharmaceutical company known for its innovative approach in diabetes treatment, and OnKure Therapeutics, an oncology-focused pharmaceutical company, have announced the termination of their global drug licensing agreement. This partnership, established to leverage vTv’s expertise in small molecule drugs targeting cancer cells, is now dissolved, signaling a major shift for both companies […]

Scorpion Therapeutics unveils promising Phase 1/2 clinical data for STX-478 in advanced solid tumors

Scorpion Therapeutics unveils promising Phase 1/2 clinical data for STX-478 in advanced solid tumors

Scorpion Therapeutics, Inc. has presented initial clinical data from its Phase 1/2 trial of STX-478, a mutant-selective PI3Kα inhibitor for the treatment of advanced solid tumors, at the European Society for Medical Oncology (ESMO) Congress 2024 in Barcelona, Spain. The data reveals that STX-478 demonstrated a potentially best-in-class inhibition profile, with significant anti-tumor activity across […]