Sobi and Apellis Pharmaceuticals report promising results for pegcetacoplan in phase 2 NOBLE study

Sobi and Apellis Pharmaceuticals report promising results for pegcetacoplan in phase 2 NOBLE study

Sobi and Apellis Pharmaceuticals, Inc. have announced encouraging one-year outcomes from the phase 2 NOBLE study, investigating the efficacy of systemic pegcetacoplan for treating post-transplant recurrence of C3 glomerulopathy (C3G) and primary immune complex membranoproliferative glomerulonephritis (IC-MPGN). These findings were presented at the European Renal Association (ERA) Congress, held from May 23-26 in Stockholm, Sweden. […]

Novartis’ atrasentan shows significant reduction in proteinuria in seasonal allergic rhinitis patients

Novartis’ atrasentan shows significant reduction in proteinuria in seasonal allergic rhinitis patients

Novartis presented compelling interim results from the Phase III ALIGN study evaluating the efficacy of atrasentan, an investigational oral selective endothelin A (ETA) receptor antagonist, in patients with IgA nephropathy (IgAN). This data was highlighted at the European Renal Association (ERA) Congress, showcasing a significant 36.1% reduction in proteinuria at 36 weeks compared to placebo, […]