The silent killer after transplant: What you need to know about graft-versus-host disease

The silent killer after transplant: What you need to know about graft-versus-host disease

Understanding Graft-Versus-Host Disease (GVHD) Graft-versus-host disease (GVHD) is a severe complication that can occur after an allogeneic stem cell or bone marrow transplant. This condition arises when the immune cells from the donor (the graft) recognize the recipient’s body (the host) as foreign and initiate an attack on various tissues. The development of graft-versus-host disease […]

MaaT Pharma commences HERACLES Phase 2 trial for MaaT013 in battle against acute graft-versus-host disease

MaaT Pharma commences HERACLES Phase 2 trial for MaaT013 in battle against acute graft-versus-host disease

MaaT Pharma, a French oncology company, has announced a significant milestone in its clinical research: the dosing of the first patient in the HERACLES Phase 2 trial for MaaT013, a microbiome restoration therapy. This trial targets steroid-resistant acute Graft-versus-Host-Disease (SR-aGvHD), a severe complication following allogeneic stem cell transplants. Acute Graft-versus-Host-Disease (aGvHD) is a major cause […]